Pubblicazioni - Giuli Dott.ssa Valentina

• Validation of the Somnotouch-NIBP noninvasive continuous blood pressure monitor according to the European Society of Hypertension International Protocol revision 2010.
  Blood Press Monit

  2015 Oct;20(5):291-4. doi: 10.1097/MBP.0000000000000124.
  
  Bilo Grzegorz, Zorzi Cristina, Ochoa Munera Juan E, Torlasco Camilla, Giuli Valentina, Parati Gianfranco
  
  Abstract
  
  OBJECTIVE:
  The present study aimed to evaluate the accuracy of the Somnotouch-NIBP noninvasive continuous blood pressure monitor according to the European Society of Hypertension International Protocol revision 2010.
  
  MATERIALS AND METHODS:
  Systolic and diastolic blood pressures were sequentially measured in 33 adults (11 women, mean age 63.5±11.9 years) using a mercury sphygmomanometer (two observers) and the Somnotouch-NIBP device (one supervisor). A total of 99 pairs of comparisons were obtained from 33 participants for judgments in two parts with three grading phases.
  
  RESULTS:
  All the validation requirements were fulfilled. The Somnotouch-NIBP device fulfilled the requirements of the part 1 of the validation study. The number of absolute differences between device and observers within 5, 10, and 15?mmHg was 75/99, 90/99, and 96/99, respectively, for systolic blood pressure and 90/99, 99/99, and 99/99, respectively, for diastolic blood pressure. The device also fulfilled the criteria in part 2 of the validation study. Twenty-seven and 31 participants had at least two of the three device-observers differences less than or equal to 5?mmHg for systolic and diastolic blood pressure, respectively. All three device-observer differences were greater than 5?mmHg in two participants for systolic and in one participant for diastolic blood pressure.
  
  CONCLUSION:
  The Somnotouch-NIBP noninvasive continuous blood pressure monitor has passed the requirements of the International Protocol revision 2010, and hence can be recommended for blood pressure monitoring in adults, at least under conditions corresponding to those investigated in our study.
  
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• Diastolic dysfunction in controlled hypertensive patients with mild-moderate obstructive sleep apnea.
  Int J Cardiol

  2015 ;187():686-92. doi: 10.1016/j.ijcard.2015.02.037.
  
  Lisi Elisabetta, Faini Andrea, Bilo Grzegorz, Lonati Laura Maria, Revera Miriam, Salerno Sabrina, Giuli Valentina, Lombardi Carolina, Parati Gianfranco
  
  Abstract
  
  BACKGROUND:
  Hypertension and severe obstructive sleep apnea (OSA) may independently contribute to left ventricular diastolic dysfunction. However, scanty data is available on this issue in hypertensives with mild-moderate OSA.
  
  METHODS AND RESULTS:
  We performed polysomnography, echocardiography and 24h ambulatory blood pressure monitoring in 115 treated essential hypertensives with suspicion of OSA. After exclusion of severe/treated OSA and/or cardiovascular disease patients, mild-moderate OSA (5 ? apnoea/hypopnoea index<30 events·h(-1)) was diagnosed in 47.3% of the remaining 91 patients, while 52.7% were free of OSA. Transmitral early (E) and late (A) peak flow velocities were assessed in 69 patients, and mitral annular velocity (E') in 53. Compared to non-OSA, mild-moderate OSA heart rate was higher (p=0.031) while E/A was lower (p<0.001) without differences in 24h mean systolic and diastolic blood pressures (125.36 ± 12.46/76.46 ± 6.97 vs 128.63 ± 11.50/77.70 ± 7.72 mmHg, respectively, NS). Patients with E'< 10 cm/s and E/A<0.8 showed a lower mean SpO2 than subjects with normal diastolic function (p=0.004; p<0.001). In a logistic regression model age, mean SpO2, daytime heart rate and nocturnal diastolic blood pressure fall were associated with altered relaxation pattern, independently from BMI and gender.
  
  CONCLUSIONS:
  In controlled hypertensives mild-moderate OSA may be associated with early diastolic dysfunction, independently from age, gender and mean blood pressure and in the absence of concentric left ventricular hypertrophy. Moreover nocturnal hypoxia may be a key factor in determining early diastolic dysfunction, under the synergic effects of hypertension and mild-moderate OSA.
  
  Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
  
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