Pubblicazioni - Colombo Dott. Jacopo

• Unexpected postpneumonectomy exertion-induced acute right heart failure.
  Tumori

  2018 Dec;104(6):NP61-NP67. doi: 10.1177/0300891618812682.
  
  Colombo Jacopo, Arendar Iryna, Pastorino Ugo, Codazzi Daniela
  
  Abstract
  
  INTRODUCTION:
  Thoracic surgery can have serious side effects. Accurate preoperative evaluation to assess which patients with anatomically resectable disease are suitable candidates for surgery is mandatory.
  
  CASE DESCRIPTION:
  A 58-year-old man, scheduled for left pneumonectomy for lung cancer, passed all the preoperative examinations suggested by guidelines and underwent the surgery. Three days after pneumonectomy, he experienced hemorrhagic shock and subsequent acute respiratory distress syndrome. Fifteen days after left pneumonectomy, he experienced exertional acute right heart failure (ARHF). We administered sildenafil and he improved, clinically and echocardiographically. During the following 2 years of follow-up, he was asymptomatic at rest but under exercise test, he developed pulmonary hypertension with echocardiographic signs of right ventricular impairment.
  
  CONCLUSIONS:
  In patients scheduled for major lung resections, preoperative stress echocardiography may give an adjunctive value to cardiopulmonary exercise test, quantifying the exercise-induced reduction in right ventricle ejection fraction and identifying asymptomatic patients at risk for postoperative ARHF.
  
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• An unexpected blood thief: the subacute presentation of a spontaneous Ilio-iliac arterio-venous fistula.
  Intensive Care Med

  2018 Nov;44(11):1953-1954. doi: 10.1007/s00134-018-5246-1.
  
  Caranzano Leonardo, Colombo Jacopo, Cartolari Roberto, Perren Andreas
  
  
  
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• Correlation between Insertion Torque and Implant Stability Quotient in Tapered Implants with Knife-Edge Thread Design.
  Biomed Res Int

  2018 ;2018():7201093. doi: 10.1155/2018/7201093.
  
  Baldi Domenico, Lombardi Teresa, Colombo Jacopo, Cervino Gabriele, Perinetti Giuseppe, Di Lenarda Roberto, Stacchi Claudio
  
  Abstract
  
  Aim:
  To evaluate the correlation between insertion torque (IT) and implant stability quotient (ISQ) in tapered implants with knife-edge threads.
  
  Methods:
  Seventy-five identical implants (Anyridge, Megagen) were inserted by using a surgical drilling unit with torque control and an integrated resonance frequency analysis module (Implantmed, W&H). IT?(N/cm) and ISQ were recorded and implants were divided into three groups ( = 25) according to the IT: low (<30), medium (30 < IT < 50), and high torque (>50). ISQ difference among groups was assessed by Kruskal-Wallis test, followed by Bonferroni-corrected Mann-Whitney -test for pairwise comparisons. The strength of the association between IT and ISQ was assessed by Spearman Rho correlation coefficient (? = 0.05).
  
  Results:
  At the pairwise comparisons, a significant difference of ISQ values was demonstrated only between low torque and high torque groups. The strength of the association between IT and ISQ value was significant for both the entire sample and the medium torque group, while it was not significant in low and high torque groups.
  
  Conclusions:
  For the investigated implant, ISQ and IT showed a positive correlation up to values around 50?N/cm: higher torques subject the bone-implant system to unnecessary biological and mechanical stress without additional benefits in terms of implant stability. This trial is registered with NCT03222219.
  
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• Sevoflurane improves respiratory mechanics and gas exchange in a case series of infants with severe bronchiolitis-induced acute respiratory distress syndrome.
  Clin Case Rep

  2018 May;6(5):920-925. doi: 10.1002/ccr3.1490.
  
  Nacoti Mirco, Colombo Jacopo, Fochi Oliviero, Bonacina Daniele, Fazzi Francesco, Bellani Giacomo, Bonanomi Ezio
  
  Abstract
  
  This report describes the successful use of a new intervention to improve respiratory mechanics and gas exchange in a relatively homogeneous group of infants with severe bronchiolitis-induced PARDS after failure of conventional treatment. These results may open a new interesting area of research and management for PARDS patients.
  
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• Light in the dark: F-FDG PET/CT in Staphylococcus aureus bacteremia of unknown origin.
  Intensive Care Med

  2018 04;44(4):488-489. doi: 10.1007/s00134-017-4994-7.
  
  Colombo Jacopo, Elzi Luigia, Treglia Giorgio, Perren Andreas
  
  
  
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• Pharmacokinetic/Pharmacodynamic Target Attainment During Extracorporeal Membrane Oxygenation: Does the Circuit Matter?
  Pediatr Crit Care Med

  2017 11;18(11):1090-1091. doi: 10.1097/PCC.0000000000001307.
  
  Colombo Jacopo, Scaffidi Ilenia
  
  
  
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• Evaluation of a New Ultrasonic Insert for Prosthodontic Preparation.
  Int J Prosthodont

  ;30(5):496-498. doi: 10.11607/ijp.5378.
  
  Baldi Domenico, Menini Maria, Colombo Jacopo, Lertora Enrico, Pera Paolo
  
  Abstract
  
  PURPOSE:
  This paper describes a new ultrasonic instrument (tipholder DB1 with crown prep tip inserts) designed to optimize prosthodontic margin repositioning and finishing.
  
  MATERIALS AND METHODS:
  The insert movement was assessed, and it was demonstrated that tipholder DB1 provides its inserts with an elliptical-like movement, making the entire insert surface able to cut. Then, 20 extracted teeth were prepared using tipholder DB1, sonic instruments, and traditional drills. Dental surface roughness produced using each of the three tools was measured using a roughness tester. Results were compared using univariate analysis of variance and Bonferroni post hoc test.
  
  RESULTS:
  The roughness produced using tipholder DB1 with crown prep insert presented no statistically significant differences compared to the roughness produced using sonic instruments and traditional drills.
  
  CONCLUSION:
  Tipholder DB1 with crown prep inserts is a promising treatment for margin repositioning and finishing.
  
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• A Commentary on Albumin in Acidosis.
  Int J Crit Illn Inj Sci

  ;7(1):12-13. doi: 10.4103/2229-5151.201959.
  
  Colombo Jacopo
  
  
  
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• Acetazolamide in Metabolic Alkalosis: Cosmetic or Therapy?
  Pediatr Crit Care Med

  2017 02;18(2):201. doi: 10.1097/PCC.0000000000001039.
  
  Colombo Jacopo, Codazzi Daniela
  
  
  
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• Predictors of Outcomes After Pediatric Cardiac Surgery: A Proposal to Improve the Vasoactive-Ventilation-Renal Score.
  Ann Thorac Surg

  2016 10;102(4):1413. doi: 10.1016/j.athoracsur.2016.02.109.
  
  Colombo Jacopo
  
  
  
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• Nutritional Status Assessment in Critically Ill Children.
  Crit Care Med

  2016 10;44(10):e1007. doi: 10.1097/CCM.0000000000001894.
  
  Colombo Jacopo, Pellicioli Isabella, Bonanomi Ezio
  
  
  
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• Ventilation-associated pneumonia and probiotics: many clues do not make evidence.
  Intensive Care Med

  2016 Sep;42(9):1511-2. doi: 10.1007/s00134-016-4366-8.
  
  Colombo Jacopo, Codazzi Daniela, Langer Martin
  
  
  
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• Multiplex Tests in Critically Ill Children With Severe Lower Respiratory Tract Infections.
  Pediatr Crit Care Med

  2016 06;17(6):586-7. doi: 10.1097/PCC.0000000000000749.
  
  Colombo Jacopo, Bonanomi Ezio
  
  
  
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• Lung Transplantation Is Much More Than Lungs and Fluids.
  Anesth Analg

  2016 09;123(3):794-5. doi: 10.1213/ANE.0000000000001375.
  
  Colombo Jacopo, Arena Angela, Codazzi Daniela
  
  
  
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• You Are Hypoalbuminemic and So You Are Sick?but What Can I Do for You? Your Amino Acid Gram Could Help Me.
  Pediatr Crit Care Med

  2016 05;17(5):479. doi: 10.1097/PCC.0000000000000696.
  
  Colombo Jacopo, Codazzi Daniela
  
  
  
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• Optimise nutrition before surgery: A family-centred intervention may be the solution.
  Aust Crit Care

  2016 May;29(2):51-2. doi: 10.1016/j.aucc.2016.03.002.
  
  Colombo Jacopo
  
  
  
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• Capnometry in children with bronchiolitis: A pathophysiological point of view.
  Respir Med

  2016 08;117():280-1. doi: 10.1016/j.rmed.2016.03.002.
  
  Colombo Jacopo, Bronco Alfio, Lippolis Valeria, Bonanomi Ezio
  
  
  
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• Difficult to wean patients.
  Aust Crit Care

  2015 Aug;28(3):122-3. doi: 10.1016/j.aucc.2015.05.006.
  
  Colombo Jacopo
  
  
  
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• What is new in critical illness and injury science? Acetazolamide in decompensated respiratory failure!
  Int J Crit Illn Inj Sci

  ;5(1):1-2. doi: 10.4103/2229-5151.152293.
  
  Colombo Jacopo
  
  
  
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• Intra-abdominal candidiasis and probiotics: we know little but it's time to try.
  Intensive Care Med

  2014 Feb;40(2):297-8. doi: 10.1007/s00134-013-3172-9.
  
  Colombo Jacopo, Arena Angela, Codazzi Daniela, Langer Martin
  
  
  
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• ?-adrenergic agonist infusion during extracorporeal lung perfusion: effects on glucose concentration in the perfusion fluid and on lung function.
  J Heart Lung Transplant

  2012 May;31(5):524-30. doi: 10.1016/j.healun.2012.02.001.
  
  Valenza Franco, Rosso Lorenzo, Coppola Silvia, Froio Sara, Colombo Jacopo, Dossi Roberto, Fumagalli Jacopo, Salice Valentina, Pizzocri Marta, Conte Grazia, Gatti Stefano, Santambrogio Luigi, Gattinoni Luciano
  
  Abstract
  
  BACKGROUND:
  We recently showed in a pig model of ex vivo lung perfusion (EVLP) that lung edema correlates with glucose consumption. We investigated whether salbutamol, a ?-adrenergic receptor agonist known to upregulate fluid transport in the lung, modulates glucose concentration in the perfusate during EVLP.
  
  METHODS:
  Lungs from domestic pigs underwent normothermic EVLP. At the end of controlled reperfusion, lungs were ventilated and perfused for 60 minutes, then randomized to salbutamol (?-Agonist) infusion or placebo (Control) for 180 minutes. Functional parameters were assessed.
  
  RESULTS:
  In the ?-Agonist group, glucose concentration decreased over time more than corresponding Control values (analysis of variance [ANOVA], p = 0.05). Mean pulmonary artery pressure (mPAP) was 16 ± 1 mm Hg in the ?-Agonist group vs 21 ± 1 mm Hg in the Controls (ANOVA p < 0.05). Baseline mPAP was correlated with the drop of mPAP after the ?-agonist infusion (R(2) = 0.856, p < 0.05). Dynamic compliance dropped from 51 ± 10 to 31 ± 6 ml/cm H(2)O in the ?-Agonist group and from 60 ± 4 to 21 ± 3 ml/cm H(2)O in the Control group (ANOVA, p < 0.05 ?-agonist vs Control). The ? partial pressure of oxygen/fraction of inspired oxygen was 418 ± 15 and 393 ± 12 mm Hg in the ?-Agonist and Control groups, respectively (t-test p = 0.106).
  
  CONCLUSIONS:
  Glucose concentration in the perfusate was affected by salbutamol. Salbutamol was associated with lower pulmonary pressures and better lung mechanics. These data suggest a possible role for salbutamol as a pharmacologic adjunct during EVLP before transplantation.
  
  Copyright © 2012 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.
  
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