Carro Dott.ssa Cristina
Pubblicazioni su PubMed
-
Enterovirus fulminant myocarditis as cause of acute heart failure in a newborn.
Int J Cardiol Heart Vasc2022 Oct;42():101093. doi: 101093.
Annoni Giuseppe, De Rienzo Francesca, Nonini Sandra, Pugni Lorenza, Marianeschi Stefano M, Mauri Luigi, Gatelli Italo, Mauri Lucia, Aresta Francesca, Bramerio Manuela, Francescato Gaia, Carro Cristina, Picciolli Irene, Nava Alice, Fanti Diana, Galli Cristina, Mosca Fabio, Martinelli Stefano, Ammirati Enrico
Guarda su PubMed
-
Analysis of a Cooperation and Interventional Model in Humanitarian Medicine.
Front Pediatr2021 ;9():705149. doi: 705149.
Marianeschi Stefano M, Uricchio Nicola, Cerri Gianandrea Bern, Ghiselli Simone, Carro Cristina, Albano Giulia, Viola Nicola
Abstract
Every year, around 15 million children, in developing countries, die or develop life-long disabilities because of congenital cardiac diseases. In this report we measure the effect of a pediatric cardiac surgery humanitarian project on the health of the individual and on the potential influence this has on the countries economy and its growing health services. We collected and analyzed data from the Italian NGO, Mission Bambini's database, including all congenital cardiac missions undertaken in Cambodia between 2012 and 2019. DALY's (Disability Adjusted Life Years) saved by the humanitarian mission were estimated and used to reflect on the impact this had on the populations economy. Progression in the local medical teams skills emulated the advancements made in the health sector of the region. Between 2012 and 2019, 128 patients underwent a congenital cardiac operation at Angkor Hospital for Children at Siem Reap, Cambodia. The median age was 6 years. The majority of the pathologies included VSD, TOF, ASD. The mean Aristotle's Complexity Score was 6. Post-operative mortality was 0.8% (1/128). The cost-effectiveness analysis identified 5.360 DALY's saved by surgery. The competency of the local team was progressive with them being able to handle more complex cases on subsequent missions. In developing Countries, performing congenital cardiac surgery cases can be carried out successfully with improvement in both the economy and the health system of the country by increasing the years and the quality of life of the working population and developing the expertise of the regional team.
Copyright © 2021 Marianeschi, Uricchio, Cerri, Ghiselli, Carro, Albano and Viola.
Guarda su PubMed
-
An alternative valve for mitral valve replacement in young children: using an NO-REACT® INJECTABLE BIOPULMONIC? prosthesis as a mitral valve replacement in a 14-month-old child.
Interact Cardiovasc Thorac Surg2022 Jun;34(6):1168-1170. doi: 10.1093/icvts/ivab274.
Carro Cristina, Marianeschi Stefano, Ghiselli Simone, Uricchio Nicola
Abstract
Mitral valve replacement in infants is challenging and there are limited alternative valves available. Since the Boston group published their first report on alternative valves for mitral valve replacement in infants, there has been a growth in the literature on the topic, mostly based on the use of a stented bovine jugular vein graft (Melody® valve). The challenges of the Melody valve are firstly in its length of 28?mm unexpanded, which has the potential to cause left ventricular outflow tract obstruction, and secondly, the valve needs mechanical dilatation, which is laborious. A modified No-React® Injectable Biopulmonic? Prosthesis (Bio Integral Surgical, Inc., Mississauga, ON, Canada) which is shorter (19?mm) and simpler in that it is self-expanding was implanted in a 14-month-old child to replace her mitral valve. The operation was successful and the short-term function of the prosthesis is good.
© The Author(s) 2021. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery.
Guarda su PubMed
-
Mid- to long-term follow-up of pulmonary valve replacement with BioIntegral injectable valve.
Eur J Cardiothorac Surg2020 Nov;():. doi: ezaa337.
Ghiselli Simone, Carro Cristina, Uricchio Nicola, Annoni Giuseppe, Marianeschi Stefano M
Abstract
OBJECTIVES:
Chronic pulmonary valve (PV) regurgitation is a common late sequela after repair of congenital heart diseases like tetralogy of Fallot or pulmonary stenosis, leading to right ventricular dilatation and failure and increased late morbidity and mortality. Timely reoperation may lead to a complete right ventricular recovery. An injectable PV allows pulmonary valve replacement, with or without cardiopulmonary bypass, under direct observation, thereby minimizing the impact of surgery on cardiac function. The aim of this study was to evaluate the feasibility and mid- to long-term clinical outcomes with this device.
METHODS:
From April 2007 to October 2019, a total of 85 symptomatic patients with severe pulmonary regurgitation or pulmonary stenosis underwent pulmonary valve replacement with an injectable stented pulmonary prosthesis. Data were collected from the international proctoring registry. Mean patient age was 26.7?years. The underlying diagnosis was repaired tetralogy of Fallot in 69.4% patients; moderate or severe pulmonary regurgitation was present in 72.9%. All patients had echocardiographic scans before the operation and during the follow-up period. A total of 54.1% patients also had preoperative/postoperative cardiac magnetic resonance imaging (MRI) or catheterization; 25.9% had off-pump implants. In 53% patients, pulmonary valve replacement was associated with the repair of other cardiac defects.
RESULTS:
Minor postoperative complications were observed in 10.8% patients. The overall mortality rate was 2.3%; mortality after valve replacement was linked to a severe cardiac insufficiency and it was not related to a prosthesis failure; 1 prosthesis was explanted from 1 patient because of endocarditis, and 6% of patients developed PV stenosis; minor complications occurred in 4.8%. The mean follow-up period was 4.8?years (2?months-12.7?years); 42% of the patients were followed for more than 5?years. Follow-up echocardiography and cardiac MRI showed a significant reduction in RV size and low gradients across the PV.
CONCLUSIONS:
An injectable PV may be implanted without cardiopulmonary bypass and in a hybrid operating theatre with minimal surgical impact. The bioprosthesis, available up to large sizes, has a low profile, laminar flow and no risk of coronary artery compression. Incidence of endocarditis is rare. The lack of a suture ring permits the implant of a relatively larger prosthesis, thereby avoiding a right ventricular outflow tract obstruction. This device permits future percutaneous valve-in-valve procedures, if needed. Results concerning durability are encouraging, and mid- to long-term haemodynamic performance is excellent.
© The Author(s) 2020. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.
Guarda su PubMed
-
When the unexpected happens: intracardiac extracorporeal membrane oxygenation venous cannula kinking.
Perfusion2021 Oct;36(7):769-771. doi: 10.1177/0267659120957838.
Mayer Alessandra, Macchini Francesco, Raffaeli Genny, Ghirardello Stefano, Schena Federico, Amodeo Ilaria, Mauri Lucia, Baracetti Chiara, Parente Valeria, Carro Cristina, Mosca Fabio, Cavallaro Giacomo
Guarda su PubMed
-
The role of primary surgical repair technique on late outcomes of Tetralogy of Fallot: a multicentre study.
Eur J Cardiothorac Surg2020 Mar;57(3):565-573. doi: 10.1093/ejcts/ezz270.
Padalino Massimo A, Pradegan Nicola, Azzolina Danila, Galletti Lorenzo, Pace Napoleone Carlo, Agati Salvatore, Palma Gaetano, Marianeschi Stefano Maria, Seddio Francesco, Cascarano Maria Teresa, Carro Cristina, Gregori Dario, Vida Vladimiro Lorenzo, Stellin Giovanni
Abstract
OBJECTIVES:
Repair of Tetralogy of Fallot (TOF) has currently excellent results with either transventricular or transatrial approach. However, it is unclear as to which has better late outcomes and what role of residual pulmonary valve (PV) regurgitation in the long term is. We report on late clinical outcomes after repair in a large series of patients with TOF, focusing on the type of surgical technique.
METHODS:
This analysis is a retrospective multicentre study on patients undergoing TOF repair in infancy. The exclusion criteria of the study were TOF with pulmonary atresia or absent PV.
RESULTS:
We selected 720 patients who had undergone TOF repair (median age 5.7?months, interquartile range 3.7-11.7). Preoperative cyanotic spells occurred in 18%. A transatrial repair was performed in 433 (60.1%) patients. The PV was preserved in 249 (35%) patients, while the right ventricular outflow tract was reconstructed with a transannular patch (60.4%) or a conduit (4.6%) in the rest of the patients. At a median follow-up of 4?years (range 1-21, 86% complete), 10 (1.6%) patients died, while 39 (6.3%) patients required surgical reoperation and 72 (11.7%) patients required an interventional procedure. The propensity match analysis showed that the incidence of postoperative complications and adverse events at follow-up were significantly increased in patients undergoing transventricular approach repair with transannular patch (P?=?0.006) and PV preservation was a significant protective factor against postoperative complications (P?=?0.009, odds ratio 0.5) and late adverse events (P?=?0.022).
CONCLUSIONS:
Surgical repair of TOF in infancy is a safe procedure, with good late clinical outcomes. However, transatrial approach and PV preservation at repair are associated with lower early and late morbidity.
© The Author(s) 2019. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.
Guarda su PubMed
-
Epicardial cardioverter-defibrillator implantation in a 4-month-old infant bridged to heart transplantation.
Interact Cardiovasc Thorac Surg2017 Nov;25(5):832-833. doi: 10.1093/icvts/ivx129.
Carro Cristina, Cereda Alberto Francesco, Annoni Giuseppe, Marianeschi Stefano Maria
Abstract
Implantable cardioverter-defibrillator (ICD) is the gold standard therapy for the prevention of sudden cardiac death. Nevertheless, ICD placement in the paediatric population is still limited because of several technical difficulties. Several implantation techniques have been proposed but experience in infants with very low weight and less than 6?months is very limited. We herein describe a case of a minimally invasive ICD epicardial implantation in a 4-month-old infant weighing 5?kg. A diagnosis of arrhythmic cardiomyopathy with left ventricular non-compaction disease with ventricular tachycardia storms, QT prolongation and Wolff-Parkinson-White pattern was made. Antiarrhythmic drugs, radiofrequency ablation and sympathetic denervation were not effective. ICD implantation was successful allowing the infant to survive and bridging to heart transplantation.
© The Author 2017. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.
Guarda su PubMed
-
Off-pump Kommerell's diverticulum resection and descending aorta replacement.
J Card Surg2016 Aug;31(8):544-5. doi: 10.1111/jocs.12794.
Nicolò Francesca, Costetti Alessandro, Carro Cristina, Marianeschi Stefano Maria
Abstract
We report the case of an unusual variation of a Kommerell's diverticulum in a left aortic arch with an aberrant left subclavian artery, associated with dilatation of the distal aortic arch, surgically treated without the use of extracorporeal circulation.
© 2016 Wiley Periodicals, Inc.
Guarda su PubMed
-
Field efficacy and safety of a combination of moxidectin and imidacloprid for the prevention of feline heartworm (Dirofilaria immitis) infection.
Vet Parasitol2008 Jun;154(1-2):67-70. doi: 10.1016/j.vetpar.2008.02.020.
Venco Luigi, Mortarino Michele, Carro Cristina, Genchi Marco, Pampurini Fabrizo, Genchi Claudio
Abstract
Throughout the end of March to beginning of May 2006, 212 owned cats and 608 owned dogs from a heavy endemic area for canine heartworm (HW) disease in northern Italy have been examined to assess HW infection prevalence. Both cats and dogs were clinically examined and blood samples were taken from each animal to be examined for HW antibody (Ab). Ab-positive cats were further examined for circulating microfilariae, HW antigens (Ag) and by echocardiography (ECHO) to assess the presence of adult worms. Dogs were clinically examined and blood samples taken from each animal were examined for circulating microfilariae and for HW Ag. Ten cats (4.7%) were found Ab positive. Of these, 6 cats were Ag positive (2.6%) and in 4 (1.8%) the worms were visualized by ECHO. HW prevalence in dogs was 36% (221/608). One hundred and seventy-six (29%) were both microfilaraemic and Ag positive, 40 (7%) had occult infections (no circulating microfilariae) and 7 (1%) were microfilaraemic but Ag negative. Upon owners' consent, 132 cats (including cats Ab and/or Ag and ECHO positive) were prophylactically treated against HW disease with an imidacloprid/moxidectin spot-on combination (10% imidacloprid/1% moxidectin) monthly administered for 6 months. Cats were re-examined for HW infection in November, 1 month after the last drug administration, and in May-June 2007, 7-8 months after the last treatment. All 122 cats found HW negative before treatment, were found negative at the two examinations at the end of study. The 4 cats Ab positive, 2 cats Ab and Ag positive and 1 Ab, Ag and ECHO positive at the beginning of treatment were found negative. Throughout the treatment, transitory hypersalivation and generic signs of annoyance were reported by owners in 6 cats (4.5%). All signs regressed spontaneously.
Guarda su PubMed
-
Ascending-to-descending aortic extra-anatomic graft.
Eur J Cardiothorac Surg2007 Oct;32(4):663.
Carro Cristina, Chabrot Pascal, Camilleri Lionel, de Riberolles Charles
Guarda su PubMed
-
Periaortic lymphoma mimicking aortic aneurysm.
Eur J Cardiothorac Surg2004 Jun;25(6):1126.
Carro Cristina, Camilleri Lionel, Garcier Jean Marc, De Riberolles Charles
Guarda su PubMed
-
Subannular left ventricular aneurysm in a patient with bicuspid aortic valve stenosis.
Ital Heart J2002 Oct;3(10):608-10.
Vanelli Paolo, Carro Cristina, Scrofani Roberto, Turiel Maurizio, Antona Carlo, Beretta Luigi
Abstract
The term "subannular" left ventricular aneurysm (LVA) implies that the aneurysm's origin is very close to the aorta. In the absence of an infective etiology, subannular LVAs are very rare among Caucasians. Only a few cases have been reported in the literature. We present the case of a patient with a subannular LVA who underwent surgery at our Institution.
Guarda su PubMed
-
[Aortic valve stenosis in the elderly: when to intervene? Opinion of the surgeon cardiologist].
Ital Heart J2002 Oct;3 Suppl 6():30S-33S.
Antona Carlo, Lemma Massimo, Gelpi Guido, Mangini Andrea, Carro Cristina
Guarda su PubMed
-
[Cardiac myxoma: surgical results and 15-year clinical follow-up].
Ital Heart J Suppl2002 Jul;3(7):753-8.
Scrofani Roberto, Carro Cristina, Villa Livio, Botta Mario, Antona Carlo
Abstract
BACKGROUND:
Among cardiac tumors myxoma is the most common benign neoplasm. The aim of this study was to review our Institution's 15-year experience with intracardiac myxoma.
METHODS:
From 1985 through 2001, 38 patients (22 males, 16 females, mean age 57.06 +/- 11.1, range 32-74 years) underwent surgical resection of a cardiac myxoma at our Institution. The tumor was located in the left atrium in 29 patients (76.3%), in the right atrium in 8 patients (21%), and in the right ventricle in 1 patient (2.6%). The duration of symptoms prior to surgery ranged from 2 to 30 days. None of the patients had a familial myxoma. The surgical approach comprised complete wide excision in all patients. The incidence of delayed death, thromboembolic complications, valve degeneration, recurrence and reoperation were reviewed and the Kaplan-Meier survival curve was elaborated.
RESULTS:
There were no perioperative deaths. Three patients (7.9%) developed postoperative neurological sequelae: transient ischemic attacks in 2 patients (5.2%) and a stroke with persistent neurological deficit in 1 patient (2.6%). One patient (2.6%) required pacemaker implantation for complete atrioventricular block. An inferior myocardial infarction occurred in 1 patient (2.6%). During the follow-up, complete in 89.4% of the patients (34 out of 38 patients, mean 96.8 +/- 68.4 months, range 1-218 months), there were 2 (5.8%) non-cardiac related deaths. All the patients underwent clinical examination and echocardiography at regular intervals (1 year): no neurological event was observed during the follow-up and 29 patients (90.6%) are in NYHA functional class I. At 15 years the event-free rate is 85.2%. At 15 years the actuarial survival for the whole group is 92%.
CONCLUSIONS:
At present, the diagnosis of myxoma is easy to make and two-dimensional echocardiography plays a major role in this field. Surgery is the gold standard treatment and the clinical long-term results are excellent.
Guarda su PubMed
-
Successful resection of an epicardial cyst.
Ann Thorac Surg2002 May;73(5):1633-4.
Scrofani Roberto, Carro Cristina, Beretta Luigi, Antona Carlo
Abstract
Cases of pericardial cyst have been reported by many authors, but the incidence of epicardial cyst originating directly from the epicardium in the pericardial cavity is extremely rare. A case of successful resection of epicardial cyst fortuitously discovered and diagnosed during cardiac operation is presented.
Guarda su PubMed
